Quinone and hydroquinone lipids
Medchemexpress LLC Vitamin D4 (22-dihydroergocalciferol) | 511-28-4 | 99.5% | C28H46O | 50 MG
Vitamin D4 (22-Dihydroergocalciferol) is a vitamin D derived from fungi. The precursor of vitamin D4 is 22,23-dihydroergosterol. It is for research use only and not sold to patients.
- Appearance: Solid
- Color: Off-white to light yellow
- Molecular weight: 398.66
- Solubility: 25 mg/mL in DMSO
Medchemexpress LLC Cetrorelix acetate | 145672-81-7 | 98.3% | 1491.09 | 25 MG
Cetrorelix Acetate is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist. It exhibits an IC50 of 1.21 nM and is utilized in various research applications, including studies on cancer cells and clinical trials for conditions such as polycystic ovarian syndrome and infertility.
- Potent GnRH receptor antagonist
- IC50 of 1.21 nM against GnRH
- Inhibits growth of ES-2 cell line at 1000 ng/ml
- Soluble in DMSO (50 mg/mL)
- Soluble in H2O (2 mg/mL)
- White to off-white solid appearance
- Molecular formula C72H96ClN17O16
- Long-term storage as powder at -80°C for 2 years or -20°C for 1 year
- Long-term storage in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC BMP-4 acetate | 1629625-47-3 | 99.3% | 1308.52 | 25 MG
BMP-4 acetate is a penetrating heparin-binding peptide with anti-inflammatory and anti-chondrogenic functions. It regulates the iNOS-IFN-IL6 signaling pathway to inhibit the expression of inflammatory proteins, effectively suppressing inflammation and alleviating various arthritis symptoms in murine chondrocytes and macrophages.
- Cell-penetrating heparin-binding peptide
- Exhibits anti-inflammatory activities
- Exhibits anti-chondrogenic activities
- Regulates iNOS-IFN-IL6 signaling pathway
- Inhibits expression of inflammatory proteins such as iNOS, COX2, IFN, and IL6
- Alleviates arthritis symptoms in murine chondrocytes and macrophages
- Useful in arthritis research
- Upregulates mRNA expression of cartilage marker genes in human articular chondrocytes
Cambridge Isotope Laboratories Vitamin E (Alpha-tocopherol) (unlabeled) CP 96% 5 mg
Vitamin E (Alpha-tocopherol) (unlabeled) CP 96% 5 mg
Medchemexpress LLC Vitamin D4 (22-Dihydroergocalciferol) | 511-28-4 | 99.5% | C28H46O | 1 MG
Vitamin D4 (22-Dihydroergocalciferol) is a Vitamin D derived from fungi, with its precursor being 22,23-dihydroergosterol. This product is intended for research use only.
- Involved in vitamin D deficiency and risk for cardiovascular disease.
- Vitamin D metabolites regulate parathyroid hormone gene transcription in vivo in rats.
- Appearance: Solid.
- Color: Off-white to light yellow.
- Soluble in DMSO at 25 mg/mL (62.71 mM), requiring sonication.
Medchemexpress LLC A11 (acetate) | 2412926-30-6 | 98.5% | 2767.16 | 5 MG
A11 acetate is an ANXA1-EphA2 interaction blocker peptide that inhibits nasopharyngeal carcinoma (NPC) cell proliferation, migration, invasion, and angiogenesis.
- Decreases ANXA1 bound to EphA2
- Increases Cbl bound to EphA2
- Decreases EphA2 levels and increases EphA2 ubiquitination
- Increases EphA2 internalization and colocalization with Cbl in NPC cells
- Inhibits NPC cell proliferation
- Inhibits migration, invasion, and angiogenesis
Medchemexpress LLC Resomelagon acetate (AP1189 acetate) | 1809420-72-1 | 99.75% | 358.35 | 25 MG
Resomelagon (AP1189) acetate is a potent, orally active melanocortin receptor (MR) agonist, primarily targeting MC1 and MC3. It induces ERK1/2 phosphorylation and Ca2+ mobilization, exhibiting anti-inflammatory activity and is indicated for research related to obesity and chronic inflammation.
- Potent, orally active melanocortin receptor (MR) agonist
- Targets MC1 and MC3 receptors
- Induces ERK1/2 phosphorylation and Ca2+ mobilization
- Exhibits anti-inflammatory activity
- Suitable for obesity and chronic inflammation research
Cambridge Isotope Laboratories Vitamin B2 (riboflavin) (13C4 99% 15N2 98%) CP 97% 1 mg
Vitamin B2 (riboflavin) (13C4 99% 15N2 98%) CP 97% 1 mg
Medchemexpress LLC (rel)-Eglumegad ((rel)-LY354740) | 176027-90-0 | 97.0% | 185.18 | 1 ML
(rel)-Eglumegad ((rel)-LY354740) is a relative configuration of Eglumegad and functions as a highly potent and selective group II (mGlu2/3) receptor agonist. This product is formulated as a 10 mM * 1 mL solution in water, ready for reconstitution, making it suitable for various research applications requiring precise control over mGlu2/3 receptor activity.
- Potent and selective group II (mGlu2/3) receptor agonist
- EC50s of 5 nM for mGlu2 and 24 nM for mGlu3 receptors
- Formulated as a 10 mM * 1 mL solution in water
- Ready for reconstitution
- Storage in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Cetrorelix Acetate | 145672-81-7 | 99.9% | 1491.09 | 5 MG
Cetrorelix Acetate (SB-75 acetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM. It inhibits the growth of ES-2 cell lines at 1000 ng/ml, demonstrating comparable antiproliferative effects to GnRH-I agonists.
- Potent gonadotropin-releasing hormone (GnRH) receptor antagonist
- Exhibits IC50 of 1.21 nM against GnRH
- Inhibits growth of ES-2 cell line at 1000 ng/ml
- Soluble in DMSO and H2O
Medchemexpress LLC Incensole Acetate | 34701-53-6 | 25 MG
Incensole acetate is a primary constituent of *Boswellia carterii* resin, known for its neuroprotective effects against neuronal damage caused by traumatic and ischemic head injuries. It has been observed to reduce Aβ25-35-triggered apoptosis in hOBNSCs. This product is intended for research use only.
- Demonstrates neuroprotective effects against neuronal damage
- Reduces Aβ25-35-triggered apoptosis in hOBNSCs
- Ameliorates Aβ 25-35-induced cell death in hOBNSCs
- Reverses increase in mRNA and protein levels of Bax, caspase 8, and cyto c
- Increases the mRNA and protein level of Bcl2 induced by Aβ 25-35 in hOBNSCs
Medchemexpress LLC VSLRGDTRG acetate | 99.4% | 960.05 | 5 MG
VSLRGDTRG acetate is a synthetic peptide containing the RGD motif from cadherin 17 (CDH17), which binds to α2β1 integrin and activates its signaling pathway. It promotes the high-affinity conformational change of β1 integrin through the RGD motif, enhancing cell adhesion and phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. VSLRGDTRG acetate can be used in research on cancers expressing CDH17, such as colon cancer and pancreatic cancer.
- Binds to α2β1 integrin and activates its signaling pathway.
- Promotes the high-affinity conformational change of β1 integrin through the RGD motif.
- Enhances cell adhesion and phosphorylation of FAK and ERK1/2.
- Drives tumor proliferation and metastasis.
- Can be used in research on cancers expressing CDH17, such as colon cancer and pancreatic cancer.
Medchemexpress LLC R5 peptide (acetate) | 99.0% | 2013.26 | 25 MG
R5 peptide (acetate) is a synthetic peptide known for its silica-precipitating activity. It is provided as a solid and is intended for research purposes only, not for patient use.
- Shows silica-precipitating activity
- Provided as a solid
- Sequence: Ser-Ser-Lys-Lys-Ser-Gly-Ser-Tyr-Ser-Gly-Ser-Lys-Gly-Ser-Lys-Arg-Arg-Ile-Leu
- Sequence shortening: SSKKSGSYSGSKGSKRRIL
- Chemical formula: C84H149N29O28.xC2H4O2